The objective of this essay is to propose an ecology of knowledge between the principles of complexity and the paradigms considered as traditional. In the first instance, a perspective of what is understood by complexity is offered, followed by a brief approach to the teaching process; finally, a systematization of concepts between the principles of complexity and the teaching process is carried out. Hermeneutics was used as a research method. In conclusion, the document integrates an epistemological dialogue that guides rethinking Education, specifically the teaching process, from a complex and transdisciplinary perspective.